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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41f39552b31ddf59db632a410ffa45e76bbe9689ce29ce5391de99afb3cce05' 
  AND token = 'pu3R34KxHFbKR7vvv3lt0P03s5tdEUae0CbRTtRbHUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}