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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd795bc8d35a78ee125c6b04aa27c834c5166b5b86b0b15ebd637e0f9411d5245' 
  AND token = 'myRpGOqGKk8MFrDy6oa9j88F5+M0F9iCdqW0UPfo/S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}