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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6c39e030a80007e3a6b568880bf1c500650a7583cd107e485471e11097089e' 
  AND token = '2vSNpcYwZ+GZMJb9F1ETLO38Jxpn/NIDVmlXu5u0XiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}