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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd2b76d468d394404106cb6994b622ad73b0d87e0263668951a35b04e9aff67' 
  AND token = 'RhASeapymcBDBYslWS/uTljDH9StYfea71egKGc/PFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}