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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf588d4ca2973a7591cece293550c771bed2247b9c2797b8bcc8ed79f3edcd28' 
  AND token = 'dzgYc40cw0POdXfYMDrSbSqkwUpCbYfK0ZdxyBeH3iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}