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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74837a047195cd1c1941cb5cd3fa3f71c1059e46e8aa60a09e7fa299bde8f64' 
  AND token = '/+W27u1MAOW+n5ih2gj1P+gHRHYZQlp4P9YMbt6O4GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}