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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413b639f20f630bd77364b1a68156924e071badf0621ba79a532ea1aa222ecfb' 
  AND token = 'Memx4MxcpwMMbKtKjqm5UL0rWlpxfVDm+Ec8hZkKuxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}