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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4311b2f3d8b50962f4eb79dfb13090f25f7d8a453c03bf269de35e9245490e24' 
  AND token = 'dqCQr2+PS5D7cFPXpG08+qfGe0HcvBzuHN31Sl2aCzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}