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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddef070aa17637a9d45f4fa941581f9fc52856d98bdc307462c41474212aa64e' 
  AND token = 'FO+GqkF1WfiYBIO/mUBdpmRcqa9kkej3471AG60WRiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}