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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e8df91bbd11b58266dafaed1630aba820333bd62ee834dfdf59580a35ae2c5' 
  AND token = 'b45HahYZSZsxAnFhZF+MsOWsc0adk/8r+aPPp7yuxEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}