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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253d14f7e5aa114a2c3940e84747073142e04d4f2c28d360f7e5f7483b62d6ac' 
  AND token = '0FSWIUx1pG8umBfo+93YJSv4f7dI8PBF195kirLGNqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}