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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3208ed053932c89df76bdc665d257a58146cb493894477e4e1870e6dd2f8010' 
  AND token = 'CVUyVfA5CwbgRHU1Qb/2R1UFaOW15qlWW/jKP4mt0qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}