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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4371fdd52a6db34cd45cf2a9fd460c5112ea3f4aa3e9c03a5798a02538376325' 
  AND token = '61kFH6UkLZL5vq9KTje9F+3e7T2CyVYDnXhzoMxe8gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}