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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8866cc744086a8cb7c6d5d37fcce761eeeb39ecd451d318418814dcab09b54' 
  AND token = 'j5B46LmKSkk+lpuPODGRa+W3b4bmW4uIX+pF3JONhWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}