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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fea498cb32ef334a42f242d0246a0c2c8eeaf5b1ba8812b7c657ce7f02657bb' 
  AND token = 'JTQz3IU9x+TTIf3v6tDpb1bcIPVIOyv6IKU2gvGhfOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}