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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d55a47a03f2a36a76696fe7d5c09fdf6cf6f05a8deb4b28167663edd35fe4f' 
  AND token = 'ITPACKE1iX2l+uDJoVgh0khCd/jegYTHbHT5dSDwlJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}