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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec66dbde75784db9fb3a0336e9e56158f5c83c6660282d6487ea1c8ea827ad1b' 
  AND token = '9HBXd+Om4MJnoPlaAM4QPZDR/VEKuxCLybuqCL14lJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}