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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd2b9b70b7b9d3518329a256baa32e64af0f8f07c72a950502bf483c0a6bd55' 
  AND token = 'xRTL2RuVAZScpAF4sYEqNd198ipFEYyWFEuS1DvQ9Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}