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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b75ea1b8985c7b1f7b7311c9c3d18683e108691d59fc7fff7ed4ad598bd9f1' 
  AND token = '2hR8ZKN1pSd65oFsgrhFYdv0Vt00xQByGSeQH3ETvIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}