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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d2a4b921b84fe668935505e7fc6813aada48abcca2e5de6b987ce2ad2acf49' 
  AND token = 'XW24MlX3yzMqcWGQCh5nlsqhX3tepWtaB0NmdD1QV4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}