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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f263f1747444749b6cb86b175606ac9face6687066269a19d28ba16e346275' 
  AND token = 'ICZNEJY4TpewrYd8JhkPBg8E5UF4h667bXm9F1CSKH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}