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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e6d7effccfb8b850079974a964dc406a3fa60112e76373e005f5ea4f74b6c2' 
  AND token = 'yAZOCCzAtXJ/W39dKuwBqZDcswVuB8XIJ/ffIark6ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}