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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67045b3bbd81df7fefeda1733799354f2c38beb35f8f58f90deed67d9f50dd2e' 
  AND token = 'AlqT3tCJwgRzKxQO7xQHrqL6bw/zRegHjah08Wt9TiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}