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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c09f135804a1a7303a47ac3b7f9a941549db20d98cb7487e8b972f6f19e494' 
  AND token = 'oX/+kZAfa/ssY5qQrLC1S+XkKWU6biLxCtwKt6M8ydg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}