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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b348b398af7e66f6ef0ac07a0ff2809df1b23c68c45e3be6712391879700c6c' 
  AND token = 'tOQGW49+t3TaIn3IXXQmXMjE5ddyfHyjdK9RV+nq51s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}