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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62211e4217b3f3c57c1127621f143efe292d8fb93dfc51f13e930086fdcc1a84' 
  AND token = 'pkVMnWaubTK0KffsfjlXg33fMIxcMHDOWMgPW3n5QMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}