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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f5a0fbec3d5280a82bb2108a5a5071543d263726c69be3afe01bb2e869f044' 
  AND token = 'hwiet9fH7cEfe4vqTKdRkQUvcznDFKrPfOQUS7KXKLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}