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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45555e3d8932705b42fdaa8938dffd66d5565944cc110200cbd4b775baf7ae80' 
  AND token = 'ro3aswNfnVM62UvQihHw9UnaRefN768VPP/E6n5UmZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}