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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3b9e90dde614bf40d8ad63319734807f8ab3c09925bdf07c2595652e570b58' 
  AND token = '29qY5cngaSBycSieGIXjwgKTunw6tP5ysXeHwDmjFgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}