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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1390933567aa7b8b9bc7c54d7b6c1f65652c4f60f9cce939a33085100222eba' 
  AND token = 'nxpyMg1ujRerVfbnkA7YJC+M2N6IDKxRY/BKKEd01UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}