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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f5709a2c1e05ae87f30ca5866386e55206d5b4a656e98e94dda5bc6a87c756' 
  AND token = 'QYDfdFpcLUShphY77h+q+eGxfbaCPzKzKjQ3DqPjq/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}