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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377439371eb871585eb65bcba4cd18ae361b98fd6c41e595e709f39baf6882db' 
  AND token = '8eeTcAWV7FOYJ7KHmjqAKo10cjN0a/KIbBjCbdu2zZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}