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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaff4db39619cfd7a4f0134f1e3d0f565a6cbbe880c862c4579192fcc9416bdc' 
  AND token = '+bsVY0HF60K+DvvD/MYY4Ht8bsIwW1IvdxFcf/b0Ekg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}