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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2644b219c0071b00774720532feca12eea1665818a66524822d4475b6378c75d' 
  AND token = '/tkulN0LNBVvLmsod4GeHfe/5QjtEoqTuHA4M6ZGHn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}