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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '013fe6e48cbb111da127c36775c238d11cf0930964830c5b03978adb0e8fb1c3' 
  AND token = 'IcDfo55m1g9dq/T/rUlS1/pCEZZ126GXEqTu52SkqTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}