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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da61dc971a7000afa2af79a74d6dd565af573271de3ce1d20c3953c9c3cd1d06' 
  AND token = 'ZlS/60Fl/jFCJ+50KqDjaQtcfA7NoolL61gD3ePwYLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}