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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54abd4a55bdd0941c1ec6628b69e8a2fdce1f8179dd220ac9b52daf49e4ce36e' 
  AND token = 'y75bdMXXQA7JkGPxxKU7+no7+hR1iKZ+i618Y2Sm9r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}