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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be149234c7c0f649ca895a9da048580e4785c46b5abbd651a2a3e4b95c5fb61' 
  AND token = 'I4Hlxz4/ORzNQkRpjyFr8IOk6/gjAu1Nlx5zTSo9aKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}