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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c438873b6fccf77e658cdadc38a013e0725c41ce156f1fea05a6eed4fe4d8fa0' 
  AND token = '1E6a7EmmKo28IGVLrL47MK7MdGSEbK1WXREUIqJhFiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}