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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194c3398a842d19ac200f6441bf17f4e139ba9f0ee964400a9b9076a606465bf' 
  AND token = 'VqH44s39dwbzMmAX4thi1OsSyqq6FNXGG4rq0rS9ips=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}