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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9468008d5fedb10583de5693317f6e29ad9890b9ebc2a62bff5adf346abb028a' 
  AND token = '+EukznFJbz6fvHjccPVuo2c7nF4Oo1C2/cl40/zc6FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}