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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac64c7248d137c717948c5786dc057c62386053aaa954ca4d1db973efce1a2f' 
  AND token = 'K44xKjamttCCaeuyjZgmAoFdMnIbLE3A2NDVxKNDSFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}