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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5096530cdb2277f156b2b291aa1993005a494f82fb12bf9530874d8fedb10d47' 
  AND token = 'TLsCx97WL/aGBZV6m1L/3z91qeXFH0gRUn7bUm/RTAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}