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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9fbf6a7e38b155d7273631aca68f85ebebdf4b6d87fcf262f183879039da34d' 
  AND token = 'ANrx5thLyefDUAIEOXciRzI0TboLXasycc70c4BflcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}