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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5248b1d7fe68187e8aa15048b0b535deeb8ea72a7daae7de7c5fb750641324b1' 
  AND token = '9XIozrCvNMeKxaziHt4P1w+zmbCynz9355ZWkGEWQBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}