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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948d6ebeb8adaf03109444e470a993915c04b1232019c4f6b0c5de2933a4e3ec' 
  AND token = '4TbFTVSgLb9dHzSnNO/eAnsspiS8V+xbla9+6LIY+Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}