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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049016e45f6a4506f2e7d46fac2cb4679e0eb8eb8e8270191c64ad8268020d96' 
  AND token = 'bO7hSu5y991YA5mq++FVri9awBNZiQtlDSkSbSBD8ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}