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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c33caef5b6248f2b37e4f45e3b787d792bc6781e7afb4d63f5a6c64c3cefbdc' 
  AND token = 'VarYYUGN8ZAuE1imEy4TSyoR4ONXuslfMQLRjH0oe7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}