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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19ba78cf869dea1d50f6aed44bbec918b8493b2afaf19546df79172d36e61010' 
  AND token = 'NXvRnbJs0LxkJFmjIOEQP4yp9MFOEJoIVXqBKuEL7AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}