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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3122468934fad5fde3ffb41a3a77b55c78413dfea10f57b2fed277897e8a7e0' 
  AND token = '6QG0p+aRMrvtMNRTgpsy/MzN/0LsWyCaImXfdXOlqy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}